Table 1.
ABO Blood Group Genotypes of Pancreatic Cancer Patients and Population Control Subjects, Urban Shanghai, China, 2006–2011
| rs8176746 × rs8176719 Genotypea | No. of Cases | Genotype Frequency in Cases, % | No. of Controls | Genotype Frequency in Controls, % | Phenotype A Alleles | Phenotype B Alleles | Phenotype AB Alleles | Phenotype O Alleles |
|---|---|---|---|---|---|---|---|---|
| AA × GG | 31 | 3.7 | 43 | 4.4 | BB | |||
| AA × GD | 1 | 0.1 | 1 | 0.1 | BOb | |||
| AC × GG | 90 | 10.6 | 110 | 11.3 | AB | |||
| AC × GDc | 184 | 21.7 | 232 | 23.9 | BO | |||
| CC × GG | 62 | 7.3 | 55 | 5.7 | AA | |||
| CC × GD | 257 | 30.4 | 222 | 22.9 | AO | |||
| CC × DD | 221 | 26.1 | 308 | 31.7 | OO |
a The rs8176719 alleles are exon 6 261G (“G”) and 261delG (“D”). The rare genotypes AA × DD and AC × DD did not occur among cases or controls. (See footnote b.)
b The AD haplotype corresponds to the rare O24, O40, or O41 alleles (8).
c The AC × GD genotype denotes either haplotypes AG and CD (the common BO alleles, respectively) or AD and CG, which haplotype is rare in the Han Chinese population.