Table 3.

Significance (corrected p values by the Sidak method) of pairwise group difference: (ab) Treatment effects on P7 volumes (N=75) and P21 volumes (N=78) without (a) and with (b) covariates. (c) Treatment effect on the P21 measure covaried for the P7 measure. Bones without any significant pairwise group difference (p>0.05) are not shown in the table. Significant results (p<0.05) are highlighted in bold.

(a) Pairwise treatment effect on P7 and P21 measures (no covariates)
Exp	Bone	No Covariates
		ALC vs CHOW	ALC vs PF	PF vs CHOW
P7 (N=75)	Skull	0.3922	0.0025	0.0187
	Parietal	0.0023	0.1606	0.1244
	HeadSize	0.0001	0.0255	0.0900
	HeadCirc	0.0002	0.1152	0.0191
P21 (N=78)	Skull	0.0000	0.0000	0.7823
	Frontal	0.0000	0.0011	0.7007
	Parietal	0.0000	0.0000	0.9082
	Occipital	0.0000	0.0000	0.1117
	Mandible	0.0043	0.0094	0.9989
	HeadSize	0.0000	0.0000	0.9987
	HeadCirc	0.0000	0.0010	0.5897

(b) Pairwise treatment effect on P7 and P21 measures (with covariates)
Exp	Bone	Covaried for sex and headsize			Covaried for sex and headcirc
		ALC vs CHOW	ALC vs PF	PF vs CHOW	ALC vs CHOW	ALC vs PF	PF vs CHOW
P7 (N=75)	Skull	0.0314	0.1234	0.0000	0.0633	0.0198	0.0000
	Mandible	0.0061	0.7702	0.0023	0.0307	1.0000	0.0015
P21 (N=78)	Skull	0.0000	0.0001	0.7501	0.0000	0.0000	0.9978
	Frontal	0.2382	0.7254	0.5906	0.0177	0.0613	0.8217
	Parietal	0.0003	0.0001	0.8618	0.0000	0.0000	0.7351
	Occipital	0.0005	0.0661	0.0531	0.0001	0.0049	0.1619

(c) Pairwise treatment effect on the P21 measure covaried for the P7 measure
Exp	Bone	Covaried for the P7 measure
		ALC vs CHOW	ALC vs PF	PF vs CHOW
P21 (N=56)	Skull	0.0000	0.0000	0.0002
	Frontal	0.0001	0.0100	0.1355
	Parietal	0.0097	0.0040	0.9936
	Occipital	0.0018	0.0697	0.0891