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RA receptor antagonists inhibit migration of precursor cells from of the ganglionic eminence to the cortex. In the slice cultures, migration of cells from the GE to cortex could be significantly inhibited by treatment with a pan-RAR antagonist (LG100814), but was not blocked by a pan-RXR antagonist (LG100849), both at a concentration of 5 μM (*control vs. RAR-antagonist t = 6.16, p = 0.0016).
