Table 1.

Demographics of patients undergoing esophagectomy.

Variable	<70 years (n=334)	70–79 years (n=124)	≥80 years (n=16)	p value
Age (years), mean±SD	57.9±7.4	73.8±2.9	82.2±1.6
Gender, n (%)				0.093
Male	278(83.2)	99(79.8)	10(62.5)
Female	56(16.8)	25(20.2)	6(37.5)
Comorbidities*, n (%)
Hypertension	129(41.1)	67(59.3)	3(23.1)	0.001
CAD	38(12.1)	29(25.7)	3(23.1)	0.003
Diabetes	41(13)	20(17.7)	0(0)	0.157
PVD	8(2.6)	6(5.3)	2(15.4)	0.029
CVA	7(2.2)	6(5.4)	0(0)	0.194
Atrial fibrillation	6(1.8)	4(3.2)	1(6.3)	0.379
Steroid use	5(1.6)	2(1.8)	0(0)	0.890
CHF	1(0.3)	0(0)	0(0)	0.818
COPD	4(1.2)	0(0)	0(0)	0.528
Pulmonary function tests
FEV1 %, mean±SD	86.9±20.2	86.2±18.2	86.6±21.2	0.962
DLCO %, mean±SD	85.0±22.9	83.7±20.6	83.5±18.9	0.897
Histology				0.947
Adenocarcinoma	261(78.1)	100(80.7)	14(87.5)
Squamous	43(12.9)	15(12.1)	2(12.5)
HGD	17(5.1)	3(2.4)	0(0)
Other malignant	13(3.9)	6(4.8)	0(0)
Stage				0.454
0	27(9.4)	7(6.2)	0(0)
IA	66(22.9)	25(22.1)	3(21.4)
IB	40(13.9)	9(8.0)	2(14.3)
IIA	0(0)	0(0)	0(0)
IIB	77(26.7)	29(25.7)	5(35.7)
IIIA	61(21.2)	34(30.1)	4(28.6)
IIIB	9(3.1)	8(7.1)	0(0)
IIIC	3(1.0)	1(0.9)	0(0)
IV	5(1.7)	0(0)	0(0)
Neoadjuvant therapy, n(%)	173(51.8)	46 (37.1)	3(18.8)	0.001

CAD: Coronary Artery Disease, CHF: Congestive Heart Failure, COPD: Chronic Obstructive Pulmonary Disease, CVA: Cerebrovascular Accident, DLCO: Carbon Monoxide Diffusing Capacity, FEV1: Forced Expiratory Volume in 1 second, PVD: Peripheral Vascular Disease

^*Comorbidities information available for 440 patients (<70 years: 314, 70–79 years: 113 and ≥80 years: 13).