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. Author manuscript; available in PMC: 2013 Aug 2.
Published in final edited form as: Surgery. 2012 Oct 24;152(6):1068–1077. doi: 10.1016/j.surg.2012.08.021

Fig 4.

Fig 4

Histological analysis of pancreata from Pdx1-Cre:Men1 floxed/floxed conditional knockout mice with monthly subcutaneous (SC) injections of PBS or pasireotide (SOM230) (160mg/Kg/month [64mg/ml]) for four months at same magnification demonstrating a significant difference in tumor size. (A) Hematoxylin and eosin (H&E) staining of representative pancreas with insulinoma from the control group receiving monthly SC injections of PBS at the end of four months at 2.5× magnification. (B) H&E staining of representative pancreas with insulinoma from the treatment group receiving monthly SC injections of SOM230 at the end of four months at 2.5× magnification. (C) Mean insulinoma size in control and treatment group after 4 months.