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. Author manuscript; available in PMC: 2013 Aug 2.
Published in final edited form as: J Immunol. 2012 Feb 6;188(6):2612–2621. doi: 10.4049/jimmunol.1102836

Figure 5.

Figure 5

Mice deficient for β-catenin in osteoclast precursors are osteopenic. (A) Microcomputed tomography (µCT) analysis of the femurs of LysM-Cre+/+ β-catenin+/+ (β-cat+/+) and LysM-Cre+/+ β-cateninfl/fl (β-catΔ̃Δ mice. Upper photographs: longitudinal view; lower photographs: axial view of the metaphyseal region. The parameters are based on the µCT analysis of the metaphyseal region of mice at the age of 6 weeks. (B–D) Histological analysis of the tibiae. (B) Photographs represent TRAP and hematoxilin staining. (C) Osteoclastic and (D) osteoblastic parameters were obtained from bone morphometric analysis of mice at the age of 6 weeks. Graphs show mean ± SEM, N=5. *, P < 0.05; **, P < 0.01.