Table 3. Scoring of disease activity index (DAI).

Weigh loss	Stool consistency	Bleeding
0: <1%	0: normal	0: negative
1: 1-5%	2: loose stools	2: positive
2: 5-10%	4: diarrhea	4: gross bleeding
3: 10-15%
4: >15%

To determine the DAI, scores for weight loss, stool consistency and bleeding were measured daily. Weight loss was calculated as the percentage difference between the body weight on day 0 and every other day of the experiment. Diarrhoea was defined as mucus/faecal material adherent to fur and bleeding was detected by occult blood test [37].