Table 2. Correlation between parameters of thrombin generation and microvesicle levels in each subject group.
| Group | TG parameter | Mean values | EMV (CD144+ve) | PMV (CD42b+ve) |
|---|---|---|---|---|
| HD | PT (nM) | 57.1±25.1 | r=0.52; p=0.02 | r=0.7; p=0.002 |
| ETP (nM) | 928±398 | r=0.53; p=0.02 | r=0.72; p=0.001 | |
| Lag time (mins) | 10.9±1.8 | r=-0.55; p=0.02 | r=-0.44; p=0.08 | |
| PD | PT (nM) | 76.7±38.5 | r=0.62; p=0.02 | r=0.56; p=0.03 |
| ETP (nM) | 1121±421 | r=0.54; p=0.04 | r=0.63; p=0.01 | |
| Lag time (mins) | 10.8±2.5 | r=-0.38; p=0.18 | r=-0.63; p=0.01 | |
| HC | PT (nM) | 34.8±18.1 | r=0.5; p=0.05 | r=0.51; p=0.04 |
| ETP (nM) | 637±314 | r=0.49; p=0.05 | r=0.51; p=0.04 | |
| Lag time (mins) | 9.3±1.6 | r=-0.23; P=0.4 | r=-0.02; p=0.94 |
PT, peak thrombin measurement; ETP, endogenous thrombin potential; EMV, endothelial derived microvesicles; PMV, platelet derived microvesicles; HD, haemodialysis; PD, peritoneal dialysis; HC, healthy controls. Data are shown, as mean±SD. Correlations were calculated using Pearson’s test.