Table 2. The summary of systemic and renal effects when EPC are delivered by HA-hydrogel embedding and transplantation as compared with conventional IV injection during AKI.

Systemic therapeutic effects	Renal therapeutic effects
Normalized mean blood pressure	Increased renal EPC engraftment
Reduced release of ALT/AST	Enhanced cortical and medullary           microcirculation
Improved competence of           endogenous stem cells	Improved proteinuria
Reduced release of pro-           inflammatory cyto-/chemokines	Improved serum creatinine
Enhanced release of anti-           inflammatory cyto-/chemokines	Decreased fibrosis
Enhanced release of pro-angiogenic           molecules