Table 2. A comparative summary of findings in high molecular weight HA vs. low molecular weight HA.

High molecular weight hyaluronan	Low molecular weight hyaluronan
- provides hydration and porosity      - sequesters and gradually releases bioactive molecules      - conceals encapsulated cells from other cells and humoral factors      - keeps stem/progenitor cells in a quiescence state      - silences inflammation      - prohibits angiogenesis      - inhibits astrocyte activation and scar formation	- activates immune response      - induces angiogenesis      - promotes proliferation, differentiation and migration of stem/progenitor cells