Table 6.
Time to progression and survival after the initial vaccination
Initial stage | Peak IgM titer to polySA | TTP (mo) | Site of progression | Survival (mo) | |
---|---|---|---|---|---|
10 μg dose level | |||||
Patient 1 | Extensive | 1,280 | 1 | Lung, LN | 3 |
Patient 2 | Extensive | 5,120 | 8 | LN, adrenal, liver | 29 |
Patient 3 | Limited | 80 | 4 | Brain, lung, LN, bone | 19 |
Patient 4 | Limited | 1,280 | N/A | N/A | 45+ |
Patient 5 | Limited | 2,560 | N/A | N/A | 72+ |
Patient 6 | Limited | 320 | N/A | N/A | 70+ |
Patient 7 | Extensive | 2,560 | 2 | Unknown | 6 |
Patient 8 | Extensive | 80 | 6 | Lung | 11 |
Patient 9 | Limited | 80 | N/A | N/A | 58 |
3 μg dose level | |||||
Patient 1 | Extensive | 0 | 5 | Brain | 11 |
Patient 2 | Limited | 160 | 3 | Unknown | 7 |
Patient 3 | Limited | 0 | 8 | Lung, adrenal | 37 |
Patient 4 | Limited | 40 | N/A | N/A | 56+ |
Patient 5 | Limited | 320 | 10 | Liver | 33 |
Patient 6 | Extensive | 320 | 2 | Brain, liver | 6 |
Patient 7 | Extensive | 0 | 4 | Lung, LN | 22 |
Patient 8 | Limited | 2,560 | 4 | LN | 13 |
Patient 9 | Limited | 2,560 | 3 | Lung, liver | 24 |
+ indicates the patient remains alive at the time of this analysis
N/A not applicable