Table 1.
Chr. | Gene | SNP ID | Region | Polymorphism |
---|---|---|---|---|
7p12 | EGFR | rs2072454 | Exon3 | C/T |
rs2227983 | Exon9 | A/G (Thr/Met) | ||
rs17337023 | Exon12 | A/T | ||
rs1050171 | Exon15 | A/G | ||
rs2293347 | Exon19 | A/G | ||
rs884225 | 3′UTR | A/G | ||
4q25 | EGF | rs11569017 | Exon15 | A/T (Val/Asp) |
rs4444903 | 5′UTR | A/G |
The SNP information is based on the database http://www.ncbi.nlm.nih.gov/SNP/
The mutation for genotypes on extrons except for rs22227983 and rs11569017 were synonymous mutations.
SNP, single-nucleotide polymorphism; EGF, epidermal growth factor; EGFR, epidermal growth factor receptor.