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. Author manuscript; available in PMC: 2014 Nov 1.
Published in final edited form as: Neurosci Biobehav Rev. 2013 Feb 21;37(0):10.1016/j.neubiorev.2013.02.008. doi: 10.1016/j.neubiorev.2013.02.008

Figure 5.

Figure 5

Dopamine signaling within the nucleus accumbens core is associated with sign tracking to a cocaine cue. Dopamine concentrations within the nucleus accumbens core were measured using FSCV during Pavlovian conditioning of a light CS with i.v. cocaine infusions. On individual trials, the peak change in dopamine concentration was positively correlated with the percent of time rats spent investigating the light CS while it was illuminated (i.e., showed sign tracking behavior). Data modified with permission from Aragona et al. (2009).