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. Author manuscript; available in PMC: 2015 Jan 1.
Published in final edited form as: Transfusion. 2013 Apr 29;54(1):179–189. doi: 10.1111/trf.12217

Figure 1. Transgenic murine RBCs express the human KEL2 antigen, and C57BL/6 recipients of KEL2 RBC transfusion make alloantibodies with KEL specificity.

Figure 1

(A) Murine RBCs from KEL2 transgenic donors were collected and stained with anti-KEL2 prior to transfusion. (B) Serum from C57BL/6 recipients transfused with KEL2 RBCs was crossmatched with murine KEL2 RBCs (solid line) or wild type C57BL/6 RBCs (shaded histogram). (C) Serum from C57BL/6 recipients transfused with KEL2 RBCs was crossmatched with murine KEL2 RBCs (solid line) or with DTT treated murine KEL2 RBCs (shaded histogram). (D) Serum from C57BL/6 recipients transfused with KEL2 RBCs was crossmatched with human RBCs expressing KEL2 (solid line) or with DTT treated human RBCs (shaded histogram); representative results are shown.