Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Model of the CusCBA tripartite efflux pump. The three components of this HME-RND system form a CusCBA efflux complex, which spans both the inner and outer membranes of E. coli to export Cu+ and Ag+ directly out of the cell (blue, CusA; green, CusB; red, CusC). The periplasmic chaperone CusF (magenta) is involved in delivering the metal ions to the CusCBA complex. Heavy-metal efflux is driven by the proton-motive force.
