Table 2. Risks for Death by Univariate Cox Regression Analysis.
| Survival Median Time, mo | Log-Rank Chi-Square Value | P value | |
|---|---|---|---|
| Sex | 3.41 | 0.12 | |
| Male | 35 | ||
| Female | 18 | ||
| Portal vein thrombosis | 4.45 | 0.03 | |
| Yes | 13 | ||
| No | 35 | ||
| Significant PHT a | 24.75 | < 0.0001 | |
| Yes | 14 | ||
| No | 48 | ||
| Ascites | 8.82 | 0.022 | |
| None | 36 | ||
| Mild-Moderate | 33 | ||
| Severe | 12 | ||
| Hepatic encephalopathy | 34.14 | < 0.0001 | |
| None | 37 | ||
| Grade 1-2 | 14 | ||
| Grade 3-4 | 1 | ||
| CLIP a score | 0.54 | 0.76 | |
| Early | 42 | ||
| Intermediate | 57 | ||
| Advanced | 35 | ||
| CPT a class | 25.2 | < 0.0001 | |
| A | 68 | ||
| B | 35 | ||
| C | 9 | ||
| AFP a , ng/mL | 3.17 | 0.075 | |
| < 400 | 42 | ||
| ≥ 400 | 22 | ||
| Age, y | 0.272 | 0.6 | |
| ≤ 65 | 36 | ||
| > 65 | 33 | ||
| Viral etiology of liver disease | 0.822 | 0.365 | |
| Yes | 36 | ||
| No | 22 | ||
| ALT a , U/L | 1.73 | 0.19 | |
| ≤ 40 | 24 | ||
| > 40 | 38 | ||
| AST a , U/L | 0.22 | 0.64 | |
| ≤ 37 | 30 | ||
| > 37 | 42 | ||
| Bilirubin, µmol/L | 16.73 | < 0.0001 | |
| ≤ 22 | 48 | ||
| > 22 | 18 | ||
| INR a | 5.4 | 0.02 | |
| ≤ 1.2 | 42 | ||
| > 1.2 | 33 | ||
| Platelet count, 109/L | 0.003 | 0.96 | |
| ≤ 150 | 35 | ||
| > 150 | 37 |
aAbbreviations: AFP, alpha-fetoprotein; ALT, alanine aminotransferase; AST, aspartate aminotransferase; CLIP, cancer of the liver Italian program score; CPT, Child-Turcotte-Pugh score; INR, international normalized ratio; PHT, portal hypertension