Figure 4.
Antibody-induced TfR1 degradation in vitro. (A) Whole-cell levels of TfR1 in a panel of malignant B cells after 12 h treatment with buffer as a control (NT), ch128.1 or ch128.1Av. (B) Quantification of whole-cell levels of TfR1 after 12 h treatment with buffer as a control (NT), ch128.1 or ch128.1Av. The ratio of TfR1, detected from a compilation of 3 independent experiments with respect to the level of GAPDH is shown, with all treatments compared to buffer treated cells. Error bars indicate standard deviations (*p < 0.05).