Figure 1.
Characterization of purified human YB-1 on gels stained by Coomassie. (Top, left) This gel contains GST–YB-1 and GST proteins purified on glutathione–Sepharose beads. (Top, right) GST–YB-1 was treated with thrombin to remove the GST portion of the fusion protein as described in Materials and Methods. The size of YB-1 is ∼42–44 kDa. (Bottom) These gels contain YB-1 proteins eluted from a Superdex-200 gel filtration column with or without 2 mM ATP in the buffer. The numbers above each gel represent the position of marker proteins eluted from such a column. The numbers below the gel represent the fraction number.