Table 3. Post-mortem data of SPF chickens infected with wild-type and mutant IBDV.
| Virus | Bursa/body weight ratioa × 1000 | HBLSb | ||||
|---|---|---|---|---|---|---|
| 7 d.p.i. | 14 d.p.i. | 21 d.p.i. | 7 d.p.i. | 14 d..p.i | 21 d.p.i. | |
| Mock | 3.9 (1.5) | 6.7 (2.1) | 6.2 (1.4) | 0.0 (0.0) | 0.0 (0.0) | 0.0 (0.0) |
| D6948 | 1.0 (0.3) | 1.1 (0.2) | 0.9 (0.2) | 5.0 (0.0) | 4.8 (0.4) | 4.6 (0.5) |
| srD6948-DACB | 1.5 (1.0) | 1.0 (0.2) | 0.9 (0.2) | 5.0 (0.0) | 5,0 (0,0) | 4,4 (0,5) |
| srD6948-1R2R | 1.7 (0.4) | 1.2 (0.3) | 1.1 (0.2) | 5.0 (0.0) | 4.8 (0.5) | 4.2 (0.4) |
aFor each chicken, the ratio between the weight of the bursa of Fabricius and body was determined. All given data are based on five chickens, at the given days post-infection (d.p.i.). SD is given in parentheses.
bHistopathological bursa lesion score (HBLS) was performed on a 0 (healthy) to 5 (completely damaged) scale, see Materials and Methods. All given data are based on five chickens, SD is given in parentheses.