Table 4.
Comparison of diplotype associations with BMI using various haplotype definitions across NPY2R in 2985 Utah subjects.
Diplotypes formed from NPY2R haplotypes below |
P-Value |
---|---|
SNPs 1-3-6 | 1.1 × 10−5 |
SNPs 1-2-3-4 | 1.4 × 10−5 |
SNPs 2-3-4-5 | 1.6 × 10−3 |
SNPs 3-4-5-6 | 3.6 × 10−11 |
SNPs 1-2-3-4-5-6 | 6.5 × 10−9 |
Adjusted for sex, age, age2, relatedness, FTO, MC4R diplotypes, and NPFFR2 diplotypes. Global F-test on BMI means.
SNP 1: rs12649641; SNP 2: rs12507396; SNP 3: rs17376826;
SNP 4: rs10461238; SNP 5: rs10461239; SNP 6: rs2880415