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. Author manuscript; available in PMC: 2013 Aug 5.

Published in final edited form as: Gut. 2009 Aug 10;58(12):1597–1605. doi: 10.1136/gut.2009.186361

Fig. 1 — a) Splenic CD3+ T cell fractions from immunized donor mice were stained with fluorescent antibodies. Rag1−/− or nude mice were injected i.p. with 4.5×10⁵ CD4+CD45RBlow CD25− T cells (Facs) from gliadin-immunized donors, or from ovalbumin (control)-immunized donors. After T cell transfer, recipients were either maintained on gfd (gliadin/gfd), or challenged with gluten (gliadin/gluten, ovalbumin/gluten). b) Changes in body weight in relation to individual starting weights of Rag1−/− mice (n=8–18 per group) during 8.5 weeks after transfer. Significantly lower weights in the gliadin/gluten vs. gliadin/gfd group (***p=0.001) or vs. ovalbumin/gfd (***p=0.001); while differences between gliadin/gfd vs. ovalbumin/gluten, although significant (⁺p<0.05), were small and transient.

Fig. 1 — a) Splenic CD3+ T cell fractions from immunized donor mice were stained with fluorescent antibodies. Rag1−/− or nude mice were injected i.p. with 4.5×10⁵ CD4+CD45RBlow CD25− T cells (Facs) from gliadin-immunized donors, or from ovalbumin (control)-immunized donors. After T cell transfer, recipients were either maintained on gfd (gliadin/gfd), or challenged with gluten (gliadin/gluten, ovalbumin/gluten). b) Changes in body weight in relation to individual starting weights of Rag1−/− mice (n=8–18 per group) during 8.5 weeks after transfer. Significantly lower weights in the gliadin/gluten vs. gliadin/gfd group (***p=0.001) or vs. ovalbumin/gfd (***p=0.001); while differences between gliadin/gfd vs. ovalbumin/gluten, although significant (⁺p<0.05), were small and transient.

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