Fig. 3. Changes of crypt/villus ratios in Rag1−/− recipients of T cells.
Duodenal sections were stained for Ki-67 to delineate the lengths of labeled proliferative (crypt) and unlabeled non-proliferative (villus) zones using image analysis software. Shown are examples for different crypt/villus (C/V) ratio scores (higher scores reflecting increased severity) derived from villus/crypt (V/C) ratios (100x). a) C/V ratio score 0 (V/C ratio >3), b) C/V ratio score 1 (V/C ratio 2.0–2.49), c) C/V ratio score 2 (V/C ratio 1.0–1.49), d) C/V ratio score 3 (V/C ratio <0.5).