Figure 2.

Schematic to accelerate progress in molecular-targeted radiation therapy. To bring upfront patient selection into radiation treatment selection, we need more predictive biomarker discovery and validation, which will increase the number of established biomarkers associated with novel therapeutics and subsequent improvement in patient outcome. CSA = clonogenic survival assays; GEMM = genetically engineered mouse models; G-1 = group 1 drugs (drugs with biomarkers); G-2 = group 2 drugs (drugs without biomarkers); RT = radiation therapy; SOC = standard of care.