Figure 1. Female SJL mice are deficient in CD4⁺CD25⁺ T cells.

Spleen cells from age-matched male and female SJL and C57BL/6 mice were analyzed by flow cytometry as described in Materials and Methods. Male and female SJL and C57BL/6 mice were compared for CD25 expression on CD4⁺ T cells. Data are representative of 4–8 independent experiments with similar results (A) and mean ± SEM (B). *p < 0.001 compared to SJL males and C57BL/6 males and females.