Table 1.
Phenotype | Sex | % § | MFI¶ |
---|---|---|---|
FoxP3+ | M | 92.4 ± 0.6 (n=4) | 386.5 ± 9.0 (n=4) |
F | 90.2 ± 0.6 (n=4) | 370.8 ± 15.0 (n=4) | |
CTLA-4+ | M | 32.9 ± 1.6 (n=8)* | 54.4 ± 4.0 (n=8)* |
F | 24.4 ± 1.8 (n=8) | 43.2 ± 1.9 (n=8) | |
CD62Lhi | M | 47.1 ± 2.8 (n=6)* | 403.2 ± 23.3 (n=6)* |
F | 34.9 ± 4.2 (n=6) | 326.7 ± 17.7 (n=6) | |
GITR+ | M | 94.7 ± 0.4 (n=5) | 99.8 ± 1.7 (n=5) |
F | 94.2 ± 0.5 (n=5) | 103.8 ± 2.7 (n=5) | |
CD103+ | M | 8.9 ± 1.2 (n=8) | 59.0 ± 3.0 (n=8) |
F | 11.4 ± 0.4 (n=8) | 55.8 ± 2.9 (n=8) | |
TNFR2+ | M | 50.8 ± 2.0 (n=8) | 90.7 ± 6.8 (n=8) |
F | 47.7 ± 1.3 (n=8) | 81.3 ± 7.0 (n=8) |
Percentages of different subpopulations within CD4+CD25+ T cells.
MFI, mean fluorescence intensity of regulatory cell markers on the surface of CD4+CD25+ T cells (CD62Lhi, GITR, CD103 and TNFR2 expression). MFI of FoxP3 and CTLA-4 represent intracellular expression.
Data expressed as means ± SEM;
P<0.05, (M, males Vs F, females).