. Author manuscript; available in PMC: 2013 Aug 5.

Published in final edited form as: Autoimmunity. 2010 Oct 1;44(3):219–228. doi: 10.3109/08916934.2010.519746

Table 1.

Phenotypic analysis of CD4⁺CD25⁺ T cells from spleens of male and female SJL mice.

Phenotype	Sex	% ^§	MFI^¶
FoxP3⁺	M	92.4 ± 0.6 (n=4)	386.5 ± 9.0 (n=4)
	F	90.2 ± 0.6 (n=4)	370.8 ± 15.0 (n=4)
CTLA-4⁺	M	32.9 ± 1.6 (n=8)^*	54.4 ± 4.0 (n=8)^*
	F	24.4 ± 1.8 (n=8)	43.2 ± 1.9 (n=8)
CD62L^hi	M	47.1 ± 2.8 (n=6)^*	403.2 ± 23.3 (n=6)^*
	F	34.9 ± 4.2 (n=6)	326.7 ± 17.7 (n=6)
GITR⁺	M	94.7 ± 0.4 (n=5)	99.8 ± 1.7 (n=5)
	F	94.2 ± 0.5 (n=5)	103.8 ± 2.7 (n=5)
CD103⁺	M	8.9 ± 1.2 (n=8)	59.0 ± 3.0 (n=8)
	F	11.4 ± 0.4 (n=8)	55.8 ± 2.9 (n=8)
TNFR2⁺	M	50.8 ± 2.0 (n=8)	90.7 ± 6.8 (n=8)
	F	47.7 ± 1.3 (n=8)	81.3 ± 7.0 (n=8)

^§

Percentages of different subpopulations within CD4⁺CD25⁺ T cells.

^¶

MFI, mean fluorescence intensity of regulatory cell markers on the surface of CD4⁺CD25⁺ T cells (CD62L^hi, GITR, CD103 and TNFR2 expression). MFI of FoxP3 and CTLA-4 represent intracellular expression.

Data expressed as means ± SEM;

P<0.05, (M, males Vs F, females).