Skip to main content
. Author manuscript; available in PMC: 2013 Dec 7.
Published in final edited form as: Angew Chem Int Ed Engl. 2012 Nov 19;51(50):12438–12443. doi: 10.1002/anie.201206797

Figure 2.

Figure 2

a) High-resolution HPLC-MS analysis reveals species whose molecular formulae provide additional constraints for structures proposed based on NMR-spectroscopic analysis of the P. pacificus exo-metabolome. b) Major components of the P. pacificus exo-metabolome derived from assembly of building blocks from carbohydrate (black), amino acid (green), and nucleoside (red) metabolism, as well as likely TCA cycle-derived succinate (magenta). Also shown is the related tRNA nucleoside, N6-threonylcarbamoyladenosine (t6A). c) Abbreviated synthesis scheme for identified P. pacificus metabolites and several non-natural stereoisomers (see Supporting Information for details)