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. Author manuscript; available in PMC: 2013 Dec 1.
Published in final edited form as: Cancer Gene Ther. 2013 May 24;20(6):336–341. doi: 10.1038/cgt.2013.25

Fig. 1. Survival study in nude rats with U87MG xenografts.

Fig. 1

Thirty-two nude rats with implanted U87MG tumors were randomly divided into 3 groups: control (Black, n=10); manual injection of RRV-CD (Green, n=11); and CED of RRV-CD (Red, n=11). Five days after tumor implantation, rats received either a simple injection or CED of RRV-CD into the brain tumor whereas control animals received CED of 0.9% normal saline. Five days after RRV administration, all the animals received intraperitoneal injections of 5-FC (500 mg/kg) daily for 7 days. Antitumor efficacy was determined as increase in median survival compared to control. Results are shown by Kaplan-Meier plots.