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| compd | R | EC50 (μM)a |
|---|---|---|
| C12 | Ph | 0.1 |
| C22 | CH3 | 6.4 |
| C23 | CH2CH3 | 0.6 |
| C24 | (CH2)2CH3 | 19.0 |
| C25 | (CH2)3CH3 | 2.1 |
| C26 | CH2(C3H5) | 6.8 |
| C27 | CF3 | 1.0 |
| C28 | 4-Cl–Ph | 2.0 |
| C29 | 4-NO2–Ph | 4.9 |
| C30 | 3,4-(OCH2O)–Ph | 0.9 |
| C31 | 2-F–Ph | 0.3 |
| C32 | 3-F–Ph | 0.1 |
| C33 | 4-F–Ph | 1.0 |
| C34 | 2-pyridyl | 22.9 |
| C35 | 3-pyridyl | 2.5 |
| C36 | 2-thiazolyl | 14.6 |
Inhibition of VSV replication in MDCK epithelial cells.
