TABLE 2.

STATE 1 TO STATE 2, ONLY PSEUDOMONAS INFECTIONS CONSIDERED^*

Event	Lower Limit	Hazard Ratio†	Upper Limit	P Value
Pseudomonas infection × CXCL1	—	—	—	0.04
Infection 1 vs. 0 | CXCL1 = 2 ng	1.46	3.33	7.61	0.004
CXCL5 per ng increase	1.02	1.10	1.18	0.01
Acute rejection overall	—	—	—	0.0005
Acute rejection ≥ 1 vs. 0	1.10	1.86	5.28	0.02
Acute rejection ≥ 1 vs. 0	1.67	2.79	15.28	<0.0001
Aspergillus overall	—	—	—	0.04
Aspergillus 1 vs. 0	1.13	1.80	2.87	0.01

^*The interaction between pseudomonas infections and bronchoalveolar lavage fluid (BALF) CXCL1 increases the risk of bronchiolitis obliterans syndrome (BOS). Greater BALF concentrations of CXCL5 also increase the risk of BOS, as do episodes of acute rejection independently of pseudomonas.

^†Hazard ratios for transition from transplantation to bronchiolitis obliterans syndrome for pseudomonas infections only.