Table 1.
Control n=6 | Salt-loaded n=8 | p value | |
---|---|---|---|
Body weight (g) | 302 ± 3 | 212 ± 14 | <0.001 |
Heart weight index (mg/g) | 3.45 ±0.09 | 5.25 ±0.14 | <0.001 |
PWTd (cm) | 0.178 ± 0.013 | 0.221 ±0.011 | < 0.05 |
ESD (cm) | 0.310 ±0.013 | 0.262 ±0.020 | n.s. |
EDD (cm) | 0.624 ± 0.016 | 0.606 ±0.003 | n.s. |
FS (%) | 50±1 | 58±3 | 0.06 |
E (cm/s) | 77±2 | 65±3 | <0.001 |
A (cm/s) | 41 ±2 | 43±3 | n.s. |
E/A | 1.93 ±0.11 | 1.57 ±0.12 | < 0.05 |
Edec slope (cm/s2) | 16±0.4 | 13±0.7 | < 0.05 |
Edec time (s) | 0.051 ±0.002 | 0.054±0.002 | n.s. |
e′ (cm/s) | 3.3 ± 0.1 | 2.9 ± 0.06 | < 0.01 |
E/e′ | 24±1 | 22±1 | n.s. |
Values are expressed as mean±SEM; PWTd, posterior wall thickness at end diastole; ESD, end-systolic diameter; EDD, end-diastolic diameter; FS, fractional shortening; E = peak early filling velocity; A=peak velocity of late filling; Edec slope = early deceleration slope; Edec time=early deceleration time; e′ = early mitral annular velocity.