Table IV.
Gene | SNP | Allele | MAF (overall) | MAF (cases) | MAF (controls) |
---|---|---|---|---|---|
ALOX5AP | RS17222814** | G→A | 0.07 | 0.02 | 0.11 |
ALOX5AP | RS17216473†† | G→A | 0.19 | 0.23 | 0.14 |
ALOX5AP | RS10507391† | T→A | 0.49 | 0.54 | 0.43 |
Three-way haplotype* | -- | -- | 0.07 | 0.02 | 0.11 |
HapB (ALOX5AP) | -- | -- | 0.11 | 0.15 | 0.07 |
ALOX5AP novel haplotype | -- | -- | 0.07 | 0.02 | 0.11 |
ROR2 | RS10820899 | G→A | 0.47 | 0.56 | 0.39 |
GLB1 | RS9861960 | G→A | 0.44 | 0.37 | 0.51 |
SNPs composing HapA (ALOX5AP) | RS4769874 | G→A | 0.05 | 0.07 | 0.03 |
RS9551963 | A→C | 0.48 | 0.43 | 0.53 | |
SNPs composing HapB (ALOX5AP) | RS9315050 | A→G | 0.11 | 0.11 | 0.11 |
RS17222842 | C→T | 0.08 | 0.09 | 0.08 | |
SNPs composing HapK (LTA4H) | 12P0557 | C→T | 0.21 | 0.19 | 0.23 |
RS2660880 | G→A | 0.06 | 0.06 | 0.05 | |
RS6538697 | T→C | 0.11 | 0.13 | 0.08 | |
RS1978331 | G→A | 0.50 | 0.51 | 0.49 | |
RS17677715 | A→G | 0.15 | 0.13 | 0.16 | |
RS2247570 | T→C | 0.34 | 0.31 | 0.36 | |
RS2660898 | T→G | 0.31 | 0.31 | 0.30 | |
RS2540482 | T→C | 0.25 | 0.26 | 0.24 | |
RS2660845 | A→G | 0.30 | 0.30 | 0.30 | |
RS2540475 | G→A | 0.22 | 0.23 | 0.20 |
Haplotype composed of the three individually associated ALOX5AP SNPs (rs17216473 (G), rs17222814 (A), rs10507391 (T)).
SNP also included in HapA
SNP also included in both HapA and HapB
SNP also included in HapB