Table 1.
Comparison of all patients taking or not taking colchicine: demographics, cardiovascular risk factors, and medication use (n = 1288). Data are percentage affected or mean ± SD.
| Characteristic | Colchicine, n = 576 |
No Colchicine, n = 712 |
|---|---|---|
| Age, yrs | 71.3 ± 11.8 | 71.3 + 11.9 |
| Sex | ||
| Male | 99.6 | 99.2 |
| Female | 0.4 | 0.8 |
| Race/ethnicity | ||
| White | 48.2 | 50.9 |
| Black | 38.3 | 32.7 |
| Hispanic | 7.2 | 6.1 |
| Pacific Islands | 1 | 0.8 |
| Asian | 1.3 | 1.1 |
| Not stated | 4.8 | 8.7 |
| Body mass index | 29.5 ± 5.6 | 29.4 ± 5.7 |
| Hypertension | 86.4 | 82.7 |
| SBP, mm Hg | 129.5 ± 19 | 128.7 ± 18.6 |
| DBP, mm Hg | 73.5 ± 13 | 72.7 ± 13.1 |
| Diabetes | 29.3 | 29.3 |
| HgbAlc, % | 6.3 ± 1.5 | 6.4 ± 2.5 |
| Hyperlipidemia | 63.9 | 64.2 |
| LDL, mg/dl | 91.6 ± 31.9 | 91.6 ± 26.6 |
| HDL, mg/dl | 46.8 ± 15.3 | 47.8 ± 14.9 |
| Kidney disease | 34.7 | 31.9 |
| eGFR, ml/min | 68.6 ± 26.2 | 67.5 ± 26.6 |
| Serum creatinine, mg/dl | 1.4 ± 0.8 | 1.5 ± 1.2 |
| Peripheral vascular disease | 7.1 | 7.6 |
| Coronary artery disease | 30.4 | 27.8 |
| Congestive heart failure | 11.7 | 10.4 |
| Coronary bypass | 4.2 | 4.8 |
| Current smoker | 11.7 | 10.5 |
| Serum urate | 7.8 ± 2.1 | 7.5 ± 2.1 |
| Statin use* | 57.2 | 57.5 |
| NSAID use* | 21.6 | 17.1 |
| Aspirin use* | 41.1 | 41 |
| Allopurinol use | 46.9 | 40.7 |
*
Subset analysis of 236 colchicine users and 339 nonusers. LDL: low-density lipoprotein; HDL: high-density lipoprotein; eGFR: estimated glomerular filtration rate; SBP: systolic blood pressure; DBP: diastolic blood pressure; NSAID: nonsteroidal antiinflammatory drugs.