Table 3.

Demographics, cardiovascular risk factors, and medication use in patients taking neither drug, allo -purinol, colchicine, or both agents (n = 1288). Data are percentage affected or mean ± SD.

Characteristic	Neither Drug, n = 423	Allopurinol, n = 289	Colchicine, n = 306	Both, n = 270
Age, yrs	72.3 ± 11.2	70.5 ± 12.8	71.0 ± 4.5	71.8 ± 11.5
Sex
Male	99.0	99.0	99.4	100
Female	1.0	1.0	0.6	0
Race/ethnicity
White	52.8	46.9	47.1	48.5
Black	32.7	32.1	35.6	41.2
Hispanic	5.9	6.2	12.1	4.4
Pacific Islands	0.7	1.0	1.0	1.1
Asian	1.7	0.3	1.6	1.1
Not stated	6.2	12.4	3.6	3.7
Body mass index	29.0 ± 5.5	30.0 ± 6.0	29.1 ± 1.1	29.9 ± 5.8
Hypertension	86.5	77.0	89.5	83.0
SBP, mm/Hg	126.9 ± 17.3	131.3 ± 19.9	128.5 ± 11.5	130 ± 18.3
DBP, mm/Hg	70.9 ± 12.9	75.4 ± 13.0	72.8 ± 8.0	74.3 ± 13.3
Diabetes	29.4	29.3	29.0	29.6
HgbAlc (%)	6.5 ± 4.4	6.46 ± 1.2	6.34 ± 1.9	6.3 ± 1.1
Hyperlipidemia	64.7	63.4	61.4	66.7
LDL, mg/dl	90.0 ± 33.3	93.9 ± 32.8	89.6 ± 9.5	93.8 ± 33.8
HDL, mg/dl	47.6 ± 13.7	48.1 ± 16.5	47.2 ± 4.5	46.3 ± 17.0
Kidney disease	42.9	15.9	41.8	26.7
eGFR, ml/min	66.0 ± 29.6	71.8 ± 27.5	69.2 ± 25.0	68.0 ± 28.5
Serum creatinine, mg/dl	1.5 ± 1.0	1.5 ± 1.4	1.3 ± 0.5	1.5 ± 0.9
Peripheral vascular disease	7.1	8.3	6.5	7.8
Coronary artery disease	33.2	20.0	34.0	26.3
Congestive heart failure	10.0	11.7	9.2	14.4
Coronary bypass	4.0	5.9	2.6	5.9
Current smoker	12.6	7.3	16	7.0
Serum urate	7.5 ± 2.1	7.5 ± 2.0	7.7 ± 0.25	7.8 ± 2.2
Statin use*	58.1	65.1	52.0	16.2
NSAID use*	19.4	17.1	23.2	52.3
Aspirin use*	36.6	42.5	45.6	41.4

^*Subset analysis of 575 patients from a single institution: 193 prescribed neither allopurinol nor colchicine, 146 prescribed allopurinol only, 125 prescribed colchicine only, 111 prescribed both drugs. LDL: low-density lipoprotein; HDL: high-density lipoprotein; eGFR: estimated glomerular filtration rate; SBP: systolic blood pressure; DBP: diastolic blood pressure; NSAID: nonsteroidal antiinflammatory drugs.