Table 1.
Participant Characteristics and Number of Vaccinations Received
| Characteristic | Intramuscular Control (n=20) | Intramuscular Vaccine (n = 100) | Intramuscular Plus EP Control (n = 8) | Intramuscular Plus EP Vaccine (n = 40) | Pa | Total (n = 168) |
|---|---|---|---|---|---|---|
| Sex | ||||||
| Male | 7 (35.0) | 54 (54.0) | 2 (25.0) | 19 (47.5) | .49 | 82 (48.8) |
| Female | 13 (65.0) | 46 (46.0) | 6 (75.0) | 21 (52.5) | 86 (51.2) | |
| Ethnicity/race | ||||||
| White, non-Hispanic | 16 (80.0) | 47 (47.0) | 8 (100.0) | 32 (80.0) | .002 | 103 (61.3) |
| African American, non-Hispanic | 3 (15.0) | 35 (35.0) | 0 (0) | 3 (7.5) | 41 (24.4) | |
| Hispanic | 1 (5.0) | 8 (8.0) | 0 (0) | 1 (2.5) | 10 (6.0) | |
| Other | 0 (0.0) | 10 (10.0) | 0 (0) | 4 (10.0) | 14 (8.3) | |
| Age, y | 30 (20–48) | 31 (18–50) | 25 (21–47) | 25 (19–41) | .002 | 29 (18–50) |
| Body mass indexb | 25.8 (17.4–39.2) | 26.3 (17.8–39.9) | 22.4 (20.5–28.6) | 24.8 (19.0–32.1) | .02 | 25.6 (17.4–39.9) |
| Vaccinations receivedc | ||||||
| First | 20 (100) | 100 (100) | 8 (100) | 40 (100) | 168 (100) | |
| Second | 19 (95.0) | 96 (96.0) | 7 (87.5) | 39 (97.5) | 161 (95.8) | |
| Third | 18 (90.0) | 91 (91.0) | 7 (87.5) | 38 (95.0) | 154 (91.7) | |
| Fourth | 18 (90.0) | 83 (83.0) | NA | NA | 101 (84.2) | |
| All | 18 (90.0) | 82 (82.0) | 7 (87.5) | 38 (95.0) | 145 (86.3) |
Data are no. (%) of subjects or median (range).
Abbreviations: EP, electroporation; NA, not applicable.
a For the comparison of the intramuscular vaccine group and the intramuscular vaccine plus EP group. Fisher exact tests are used for comparisons by sex and ethnicity race (white, non-Hispanic vs other). Wilcoxon rank sum tests are used for age and body mass index comparisons.
b Calculated as the weight in kilograms divided by the height in meters squared.
c Sixteen participants permanently discontinued vaccinations, and an additional 7 in intramuscular arms missed ≥1 vaccination.