Figure 7.

Transient transfection assays. HeLa cells were transiently co-transfected with the indicated promoter constructs along with IRF-1 for 24 h. (A) Schematic diagram showing different luciferase reporter constructs. Open boxes represent exons. The putative IFN-related regulatory elements GAS and ISRE are indicated; (B) P1-Luc; (C) P2-Luc. Data shown here are representative of three independent measurements. Results are expressed as fold induction relative to the activity of the empty reporter vector control and represent the mean ± SE (n = 3).