Table 1. Patient and Tumor Characteristics.
Subcategory | n (%) | |
Age (years) | ||
<50 | 20 (22%) | |
≥50 | 72 (78%) | |
median (range) | 57 (31–79) | |
Sex | ||
female | 31 (34%) | |
male | 61 (66%) | |
KPS | ||
90–100 | 76 (83%) | |
70–80 | 13 (14%) | |
<70 | 2 (2%) | |
Working/Not Working | ||
W | 77 (84%) | |
NW | 15 (16%) | |
RPA | ||
3 | 19 (21%) | |
4 | 49 (53%) | |
5 | 24 (26%) | |
Extent of Surgery | ||
Gross total resection | 32 (35%) | |
Subtotal resection | 44 (48%) | |
Biopsy only | 16 (17%) | |
Bevacizumab at 1st recurrence | ||
Yes | 29 (41%) | |
No | 33 (47%) | |
Concurrent temozolomide | ||
Yes | 83 (90%) | |
No | 9 (10%) | |
Adjuvant temozolomide | ||
Yes | 69 (75%) | |
No | 18 (20%) | |
Corticosteroids during RT | ||
Yes | 67 (73%) | |
No | 25 (27%) | |
Levetiracetam during RT | ||
Yes | 56 (61%) | |
No | 36 (39%) | |
Hemisphere | ||
right | 38 (41%) | |
left | 53 (58%) | |
both | 1 (1%) | |
Location | ||
Temporal | 23 (25%) | |
Parietal | 18 (20%) | |
Frontal | 22 (24%) | |
Occipital | 2 (2%) | |
Temporal-Parietal | 5 (5%) | |
Occipital-Parietal | 6 (7%) | |
Frontal-Temporal | 6 (7%) | |
Frontal-Parietal | 4 (4%) | |
Other | 5 (5%) | |
Failures | ||
central | 49 (88%) | |
marginal | 4 (7%) | |
distant | 3 (5%) | |
Tumor Location | ||
Periventricular | 27 (29%) | |
Nonperiventricular | 59 (64%) | |
Unsure | 6 (7%) |
Abbreviations: KPS, Karnofsky Performance Status; W, Working; NW, Not working; RPA, Recursive Partitioning Analysis; RT, Radiation Therapy. Patient demographics, treatment details, and characteristics of primary tumor before surgery/chemoirradiation.