Table 3. Study Characteristics (RADIOTHERAPY).
| Author (Year) | Country | Study | Follow-up | Patient Characteristics | Radiotherapy | Implant Characteristics | QS | |||||
| Mean Age | CON/STY | F | Time | Dose (Gy) | CON/STY | Position (Mand./Max.) | FC/FS | |||||
| Esser, 1997 | Germany | Prospec | NA | (37–79 yr) | NA/NA | 9 | BP | 60 | 66/152 | Mandible | 7/33 | 7 |
| Werkmeister, 1999 | Germany | Retro | 3 yrs | 55 yr | 17/12 | 6 | BP | 54 | 79/30 | Local: 64/Grafted: 45 | 19/8 | 7 |
| Keller, 1999 | USA | Retro | 12 yrs | (15–73 yr) | 52/2 | NA | NA | 55 and 61 | 237/11 | Grafted maxilla | 33/0 | 10 |
| Shaw, 2005 | UK | Retro | 3.5 yr | 58 yr | 43/34 | 32 | BP | 40–66 | 192/172 | Local: 238/Grafted: 126 | 25/31 | 9 |
| Yerit, 2006 | Austria | Prospec | 5.4±3.2 yr | 58±14 yr | NA/NA | 15 | BP | 50 | 162/154 | Local: 238/Grafted: 78 | 15/29 | 9 |
| Schepers, 2006 | Netherlands | Retro | up to 23 m | 66.11 yr | 27/21 | 19 | AP | 60–68 | 78/61 | NA | 0/2 | 8 |
| Landes, 2006 | Germany | Prospec | 36 m | 63 yr | 11/19 | 8 | BP | 57 | 42/72 | NA | 0/1 | 8 |
| Nelson, 2007 | Germany | Prospec | 10.3 yr | 59 yr | NA/29 | 30 | BP | up to 72 | 311/124 | 281/154 | 4/7 | 7 |
| Alsaadi, 2008 | Belgium | Retro | 2 yr | NA | 410/2 | 240 | NA | NA | 1,499/15 | 698/816 | 98/3 | 8 |
| Schoen, 2008 | Netherlands | Prospec | 12 m | 62±11 yr | 16/19 | 15 | AP | 60.1±7.7 | 64/76 | Local bone | 2/2 | 9 |
| Klein, 2009 | Germany | Retro | 5 yr | 58.4 yr | 16/27 | 12 | BP | <50 or ≥50 | 74/116 | Local: 62/Grafted: 128 | 12/13 | 8 |
| Cuesta-Gil, 2009 | Spain | Prospec | / | 52 yr | 32/79 | 31 | Mixed | 50–60 | 311/395 | Local: 454/Grafted: 252 | 6/75 | 9 |
| Salinas, 2010 | USA | Retro | 41.1 | NA | 18/26 | 19 | Mixed | > 60 | 116/90 | Local: 105/Flap: 114 | 8/23 | 10 |
| Linsen, 2012 | Germany | Prospec | 48±34.3 m | 56±16 yr | 32/34 | 23 | BP | 36 or 60 | 135/127 | 213/49 | 6/8 | 10 |
| Jacobsen, 2012 | Switzerland | Retro | 67 m | 52.4 yr | NA/NA | 16 | AP | NA | 93/47 | Local: 41/Flap: 99 | 14/14 | 9 |
| Fenlon, 2012 | UK | Retro | / | NA | 29/12 | NA | AP | 66 | 110/35 | Grafted bone | 3/15 | 8 |
CON = control group,that is non-radiotherapy group; STY = study group, that is radiotherapy group; F = Female; BP = before placement; AP = after placement; Mand. = mandible; Max. = maxilla; Retro = retrospective study; Prospec = prospective study; yr = year; m = month; NA = not available,; Local = local bone; Grafted = grafted bone; FC = failure implant number of Control Group; FS = failure implant number of Study Group; QS = quality assessment score.