Table 1. The mean value and standard deviation of the R1, R2 and PD values in various regions of interest, defined by using the PickAtlas.

ROI	R1	R2	PD	R1 slope	R2 slope	PD slope
	(s−1)	(s−1)	(%)	(s−1/year)	(s−1/year)	(%/year)
Lateral ventricles	0.38±0.32	3.89±2.35	94.3±8.8	−0.0075	−0.046	0.17
Insula	0.80±0.07	8.94±0.73	83.1±1.5	−0.0004	−0.006	0.00
Cingulate cortex	0.97±0.05	10.23±0.36	79.9±1.0	−0.0007	−0.005	0.01
Caudate nucleus	1.00±0.15	10.61±1.51	80.3±2.8	−0.0088	−0.091	0.15
Cortical gray matter	1.04±0.09	9.87±0.44	75.1±2.4	0.0031	−0.006	−0.03
Pons	1.24±0.07	11.34±0.50	73.5±1.5	−0.0003	0.005	0.00
Putamen	1.25±0.05	13.07±0.42	75.2±1.6	0.0008	0.001	−0.03
Mid brain	1.28±0.05	11.93±0.33	73.2±0.9	−0.0010	−0.007	0.01
Thalamus	1.33±0.07	12.81±0.21	72.5±1.9	−0.0016	−0.009	0.04
Occipital white matter	1.33±0.04	11.80±0.26	71.2±1.1	−0.0005	−0.004	0.00
Frontal white matter	1.33±0.06	11.77±0.32	71.1±1.4	−0.0040	−0.016	0.08
Parietal white matter	1.34±0.05	11.76±0.25	71.0±1.2	−0.0002	0.000	0.01
Sublobar white matter	1.37±0.08	11.20±0.46	69.2±1.9	−0.0043	−0.026	0.10
White matter	1.38±0.05	11.79±0.26	70.0±1.0	−0.0023	−0.011	0.05
Corpus callosum	1.39±0.27	10.71±1.58	68.3±5.6	−0.0084	−0.057	0.16

Added are the linear regression slopes with subject age. Significant slopes (p<0.05) are displayed in bold face.