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. 2013 Aug 5;8(8):e71997. doi: 10.1371/journal.pone.0071997

Figure 7. Pdk2 or Pdk4 knockdown has no significant effect on insulin tolerance in IrsLDKO mice.

Figure 7

A, Insulin tolerance tests were performed on IrsLDKO mice (n = 4–5) that were injected with shGFP, shPdk2, and shPdk4 adenoviruses. B, Area under curve was analyzed for the above ITT data. C–F, Akt phosphorylation was analyzed in the liver and skeletal muscle of mice injected with shGFP, shPdk2, and shPdk4 adenoviruses. Western blot signals were also quantified using the Quantity One software. Data are presented as means ± SEM. *, P<0.05 relative to corresponding controls.