Table 3.
Comparison of BrdU between control (pLKO.1) and treatment (shCDK4) groups
|
Cell line |
Vector |
6 hr |
12 hr |
24 hr |
||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Mean* | std | P-value† | Mean | std | P-value† | Mean | std | P-value† | ||
| MCF10A |
pLKO.1 |
5.629 |
3.740 |
0.1124 |
2.669 |
0.956 |
0.3790 |
0.944 |
0.571 |
0.9577 |
| |
shCDK4 |
2.807 |
2.460 |
1.165 |
1.628 |
0.855 |
0.689 |
|
||
| MDA-MB-468 |
pLKO.1 |
1.619 |
0.614 |
0.7841 |
1.229 |
1.030 |
0.9942 |
6.503 |
7.950 |
0.0828 |
| |
shCDK4 |
0.842 |
0.915 |
1.208 |
0.946 |
1.254 |
1.685 |
|||
| MDA-MB-231 |
pLKO.1 |
1.698 |
0.870 |
0.8941 |
1.578 |
1.634 |
0.1996 |
1.097 |
0.562 |
0.5523 |
| shCDK4 | 1.806 | 0.731 | 2.654 | 3.050 | 1.581 | 0.173 | ||||
* Mean (standard deviation) of the fold change to no radiation.
† P-value is for comparing in the mean fold change no radiation between control and treatment groups.