Table 4.
Comparison of phospho-Histone 3 between control (pLKO.1) and treatment (shCDK4) groups
| Cell line | Vector |
0 Gy |
2 Gy |
4 Gy |
||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Mean* | std | P-value† | Mean | std | P-value† | Mean | std | P-value† | ||
| MCF10A |
pLKO.1 |
1.229 |
0.530 |
0.145 |
1.737 |
0.278 |
0.277 |
0.823 |
0.587 |
0.168 |
| shCDK4 |
2.001 |
0.961 |
1.560 |
0.385 |
1.498 |
0.891 |
||||
| MDA-MB-468 |
pLKO.1 |
0.476 |
0.555 |
0.462 |
0.808 |
0.171 |
0.256 |
0.799 |
0.221 |
0.249 |
| shCDK4 |
0.509 |
0.077 |
0.654 |
0.330 |
0.979 |
0.359 |
||||
| MDA-MB-231 |
pLKO.1 |
0.168 |
0.160 |
0.324 |
0.170 |
0.176 |
0.084 |
0.060 |
0.104 |
0.181 |
| shCDK4 | 0.342 | 0.593 | 0 | 0 | 0.257 | 0.315 | ||||
* Mean (standard deviation) of % of phospho-Histone 3 positive cells.
† P-value is for comparing in the mean between control and treatment groups in each irradiation dosage.