Table 5.
Comparison of γ-H2AX between control (pLKO.1) and treatment (shCDK4) groups
| Cell line | Vector |
6 hr |
12 hr |
24 hr |
||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Mean* | std | P-value† | Mean | std | P-value† | Mean | std | P-value† | ||
| MCF10A |
pLKO.1 |
3.964 |
1.839 |
0.4621 |
3.926 |
3.203 |
0.1512 |
1.308 |
0.357 |
3.964 |
| shCDK4 |
2.803 |
2.216 |
1.583 |
1.393 |
1.707 |
0.643 |
||||
| MDA-MB-468 |
pLKO.1 |
2.148 |
1.176 |
0.8272 |
1.831 |
0.091 |
0.9269 |
4.835 |
5.890 |
0.1292 |
| shCDK4 |
1.660 |
2.104 |
1.626 |
1.407 |
1.273 |
0.729 |
||||
| MDA-MB-231 |
pLKO.1 |
2.518 |
0.443 |
0.4119 |
3.016 |
1.634 |
0.6689 |
1.587 |
0.562 |
0.6609 |
| shCDK4 | 3.710 | 2.273 | 3.630 | 3.050 | 2.217 | 0.173 | ||||
* Mean (standard deviation) of the fold change to no radiation.
† P-value is for comparing in the mean fold change no radiation between control and treatment groups.