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. 2013 Aug 5;8(8):e71231. doi: 10.1371/journal.pone.0071231

Table 2. Characteristics of matched cases and controls.

Characteristic Cases Controls p value
Number (N) 140 270 N/A
rs2794521, C allele freq 41/201* = 16.9% 92/254 = 26.6% 0.008**
rs3091244, T allele freq 87/169 = 34.0% 101/281 = 26.4% 0.050
rs3093068, G allele freq 20/246 = 8.1% 16/366 = 4.4% 0.078
rs876538, T allele freq 40/280 = 14.3% 119/440 = 27% 0.010
Age, mean years (SD) 23.88 (6.4) 23.74 (5.40) 0.768***
Parity (N,% nulliparous) 94/140 (67.1%) 114/270 (42.2%) <0.001****
Weight at first prenatal 181.7 (46.82) 161.6 (41.35) <0.001***
Body-Mass index (BMI) 30.92 (7.39) 27.42 (6.88) <0.001***
Gestational diabetes, N (% yes) 15/122 (12.3%) 9/199 (4.8%) 0.031****
Weeks of gestation at delivery 36.67 (3.96) 39.52 (1.82) <0.001***
Birth weight of infant, grams 3013 (967) 3431 (623) <0.001***
Mother's educational attainment (years of education) 11.95 (1.85) 12.15 (2.44) 0.405***
Maternal smoking, N (% yes) 38/95 (40.0%) 76/160 (47.5%) 0.543****
Maternal smoking (Mean cigarettes smoked) 6.75 (18.03) 10.51 (23.20) 0.047***
Mean systolic blood pressure 163.8 (18.3) 132.9 (12.9) <0.001***
Mean diastolic blood pressure 97.6 (10.1) 78.6 (8.4) <0.001***

*41/201 indicates 41 minor alleles (T in this case) and 201 major alleles for a total of 242.

**Differences in allele frequency evaluated with Chi square test.

***Differences between means evaluated with paired t test.

****Differences between discrete variables evaluated with McNemar's Chi square test.