Table 3. Genotypes associated with case/control (matched-pair) status.
| Discord pairs* | Discord pairs | ||||||||
| dbSNP | allele | Maj Dom | Alter | p value | allele | Min Dom | alter | p value | total pairs |
| rs12068753 | T | 28 | 15 | 0.07 | A | 0 | 0 | NA | 177 |
| rs1341665 | G | 33 | 33 | 0.90 | A | 24 | 21 | 0.77 | 152 |
| rs12084589 | C | 27 | 15 | 0.09 | A | 0 | 0 | NA | 176 |
| rs3093059 | T | 0 | 0 | NA | C | 28 | 15 | 0.07 | 177 |
| rs2794521 | T | 7 | 5 | 0.77 | C | 25 | 51 | 0.004 | 153 |
| rs3091244 | C | 59 | 29 | 0.002 | T | 13 | 24 | 0.10 | 177 |
| rs1800947 | C | 1 | 0 | 1.00 | G | 16 | 8 | 0.15 | 172 |
| rs3093068 | C | 0 | 0 | NA | G | 29 | 13 | 0.021 | 163 |
| rs3093070 | A | 0 | 0 | NA | C | 3 | 3 | 0.68 | 145 |
| rs876538 | C | 8 | 6 | 0.789 | T | 40 | 82 | <0.001 | 270 |
| risk score** | yes | 57 | 20 | <0.001 | |||||
| Severe Cases and Controls | |||||||||
| rs12068753 | T | 19 | 11 | 0.201 | A | 0 | 0 | NA | 117 |
| rs1341665 | G | 21 | 18 | 0.749 | A | 14 | 13 | 1.0 | 95 |
| rs12084589 | C | 18 | 11 | 0.265 | A | 0 | 0 | NA | 116 |
| rs3093059 | T | 0 | 0 | NA | C | 19 | 11 | 0.201 | 117 |
| rs2794521 | T | 5 | 5 | 0.752 | C | 19 | 35 | 0.041 | 106 |
| rs3091244 | C | 34 | 23 | 0.185 | T | 11 | 17 | 0.348 | 117 |
| rs1800947 | C | 0 | 0 | NA | G | 9 | 5 | 0.423 | 115 |
| rs3093068 | C | 0 | 0 | NA | G | 22 | 9 | 0.031 | 108 |
| rs3093070 | A | 0 | 0 | NA | C | 3 | 2 | 0.149 | 102 |
| rs876538 | C | 7 | 6 | 1.0 | T | 31 | 58 | 0.006 | 186 |
| risk score | yes | 41 | 12 | 0.0001 | 108 | ||||
*“Discord pairs” indicates the number of case/control pairs that are discordant for a particular genotype “Maj Dom”: where the major allele is dominant for the case. “Alter” indicates the alternate situation where the control genotype is dominant for the major allele. Similarly “Min Dom” indicates discordant pairs where the case genotype is dominant for the minor allele. “Total pairs” shows the total number of matched pairs, including both concordant and discordant pairs. “NA” refers to “not applicable”.
**Risk score indicates the risk genotype from either rs3093068 (G allele dom) or rs876538 (C allele recess) is present, among pairs with both alleles available.