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. 2013 Aug 5;8(8):e71231. doi: 10.1371/journal.pone.0071231

Table 5. Multivariate, conditional logistic regression analysis of factors associated with pre-eclampsia and severe pre-eclampsia.

Pre-eclampsia Severe Pre-eclampsia
MODEL 1, all of following *
OR P value OR P value
Age at delivery 1.053 0.076 1.052 0.166
Nulliparous 5.600 0.001 4.170 0.001
BMI 1.061 0.002 1.059 0.001
Gestational diabetes 1.684 0.278 2.241 0.166
MODEL 2, Age, nulliparity,and BMI,plus each of the following individually:**
CRP, rs3093068, (G allele additive) 1.904 0.124 2.587 0.050
CRP. rs3093068, (G allele recessive) N.A. N.A.
CRP, rs3093068, (G allele dominant) 1.904 0.124 2.587 0.050
CRP, rs876538, (C allele additive) 1.524 0.060 1.319 0.271
CRP, rs876538, (C allele recessive) 1.583 0.066 1.380 0.267
CRP, rs876538, (C allele dominant) 0.532 0.404 0.699 0.637
rs3093068,(G dom) and rs876538 (C recess) additive risk score, both  = 2, either  = 1, neither  = 0 1.779 0.016 2.035 0.013

*Covariates showing univariate significance, plus age, which interacts with nulliparity.