Table 5. Multivariate, conditional logistic regression analysis of factors associated with pre-eclampsia and severe pre-eclampsia.
Pre-eclampsia | Severe Pre-eclampsia | |||
MODEL 1, all of following * | ||||
OR | P value | OR | P value | |
Age at delivery | 1.053 | 0.076 | 1.052 | 0.166 |
Nulliparous | 5.600 | 0.001 | 4.170 | 0.001 |
BMI | 1.061 | 0.002 | 1.059 | 0.001 |
Gestational diabetes | 1.684 | 0.278 | 2.241 | 0.166 |
MODEL 2, Age, nulliparity,and BMI,plus each of the following individually:** | ||||
CRP, rs3093068, (G allele additive) | 1.904 | 0.124 | 2.587 | 0.050 |
CRP. rs3093068, (G allele recessive) | N.A. | N.A. | ||
CRP, rs3093068, (G allele dominant) | 1.904 | 0.124 | 2.587 | 0.050 |
CRP, rs876538, (C allele additive) | 1.524 | 0.060 | 1.319 | 0.271 |
CRP, rs876538, (C allele recessive) | 1.583 | 0.066 | 1.380 | 0.267 |
CRP, rs876538, (C allele dominant) | 0.532 | 0.404 | 0.699 | 0.637 |
rs3093068,(G dom) and rs876538 (C recess) additive risk score, both = 2, either = 1, neither = 0 | 1.779 | 0.016 | 2.035 | 0.013 |
*Covariates showing univariate significance, plus age, which interacts with nulliparity.