Figure 2.

Example of inconsistencies of chemical representations within the GO. Arrows represent is_a relationships between terms. A) The representation of ‘glucose-6-phosphate’ in the transport portion of the biological process graph. ‘Glucose-6-phosphate’ is inherently both a ‘glucose’ AND a ‘hexose phosphate’ B) The representation of ‘glucose-6-phosphate’ in the transporter portion of the molecular function graph. ‘Glucose-6-phosphate’ is inherently a ‘hexose phosphate’ but NOT a ‘glucose’. Only relevant terms and their relationships are shown.