Figure 1.

Designation of DUS overlapping and DUS-associated sequences, as exemplified by the Neisseria DUS. The DNA uptake sequence 5′-GGCCGTCTGAA-3′ is marked in red. Oligomers that physically overlap with the DUS are termed DUS-overlapping sequences and are marked in blue. Oligomers that are mutated in one or more of the 10 bp DUS (green denotes the mutation in the examples given) are called DUS-like sequences and are marked in orange. DUS overlapping each other with one DUS located on each strand were not detected (the Neisseria sp.) or could not occur (H.influenzae). DUS-overlapping sequences were excluded from the analysis, while the DUS-like sequences were included among the control sequences.