Figure 5. A representative TRAP staining image of femurs with segmental defect treated with a 2.5-mm scaffold containing testosterone, BMP-2 or both at day 35 after osteotomy.

Red arrows point to multinucleated osteoclasts. Quantification of osteoclasts (stained in red) in sections from the BMP-2 (5 µg), testosterone (100 µg), or testosterone plus BMP-2 treated groups is shown in the histogram below the image. N.D.: not determined.