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. Author manuscript; available in PMC: 2013 Dec 1.
Published in final edited form as: ChemMedChem. 2012 Oct 11;7(12):2093–2100. doi: 10.1002/cmdc.201200352

Figure 4.

Figure 4

Effects of drugs, 2g and GBR 12909, on locomotor activity (horizontal activity, HACTV). Rats were injected (i.p.) with either vehicle or 2g followed by measurement of locomotor activity for one and a half an hour post administration of drugs. GBR 12909 is shown for comparison from our previous work (ref). a) This time frame represents measurement of locomotor activity for ½ h after post 1 h of administration of drugs and mimicked the condition of rat FST test. One way ANOVA analysis demonstrates non significant effect between control and the dose of 2g but significant effect between control and GBR 12909 : F (3,95) = 6.73 (P< 0.05). b) This time frame represents total locomotor activity for one and a half an hour post administration of drugs. One way ANOVA analysis demonstrates non significant effect between control and the dose of 2g but significant effect between control and GBR 12909 : F (3,95) = 24.21 (P< 0.01). Asterisks indicate a statistically significant difference toward control group that received saline i.p. **P < 0.01. Each treatment group contains three to four rats.