Table 2.
Incidence and multiplicity of gastric tumors in MNU-treated mice
| Group | Effective number | Treatment |
Incidence (%) |
Multiplicity (no. of tumor/mouse) |
||||
|---|---|---|---|---|---|---|---|---|
| Adenoma | Carcinoma | Total tumor | Adenoma | Carcinoma | Total tumor | |||
| A |
21 |
MNU |
3(14.3) |
13(61.9) |
13(61.9) |
0.1 ± 0.4a |
0.8 ± 0.7 |
0.9 ± 0.8 |
| B |
4 |
MNU + H. pylori |
4(100)b |
4(100) |
4(100) |
1.5 ± 0.6 |
1.8 ± 1.0 |
3.3 ± 1.0c |
| C |
14 |
MNU + 10% NaCl |
2(14.3) |
6(42.9) |
7(50.0) |
0.2 ± 0.6 |
0.8 ± 1.0 |
1.0 ± 1.2 |
| D | 9 | MNU + H. pylori + 10% NaCl | 4(44.4) | 8(88.8) | 9(100)d | 0.4 ± 0.5e | 2.1 ±1.4d | 2.6 ± 1.1d |
Values for multiplicity are expressed as means ± SD. Incidences were generally assessed by Chi-square test, followed by pairwise analysis with Bonferroni correction. Multiplicities were generally analyzed by ANOVA, followed by the Tukey test for multiple comparison. aP < 0.01 vs. Group B, bP < 0.01 vs. Group A, cP < 0.05 vs. Group A, dP < 0.05 vs. Group C, eP <0.05 vs. Group B.